Saints could face Bolton
Southampton need to beat Millwall in their FA Cup fourth round replay to set up a tie with Bolton Wanderers.
A late Darius Henderson goal cancelled out Rickie Lambert's opener to set up a replay at St. Mary's.
The winners of the tie, which will be played on Tuesday 7 February, will face Premier League side Bolton Wanderers.
Bolton are having a difficult season in the Premier League and sit just one point above the relegation zone in 17th.
The Trotters traveled to St. Mary's last season, and left victorious when they beat the south coast outfit 1-0 to progress to the third round of the Carling Cup.
The fifth round tie will be played on the weekend of the 18th February.