Southampton reserves take on QPR at Staplewood at 7pm tonight.
Southampton top the table and another win tonight would edge Saints closer to the title.
8 first team players are available including Leon Best who has recently returned from a loan spell at Yeovil.
Henderson told the official site: 'I have not really looked at the league table. We just play the games and make sure we do it right and then results take care of themselves.
'Although it would be nice to win it, the most important thing is to develop players and to give match practice to those who need it.
Saints Res: Bialkowski, James, Pele, Lancashire, Cranie, Belmadi, Licka, Idiakez, Dyer, Wright-Phillips, Best, Mills, Rudd, Dutton-Black, White, Baseya, Poke.
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